BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations
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Aims: BMP9 is a high affinity ligand of ALK1 and endoglin receptors that are mutated in the rare genetic vascular disorder hereditary hemorrhagic telangiectasia (HHT). We have previously shown that loss of Bmp9 in the 129/Ola gen... ...
