MDM2 regulates the stability of AR, AR-V7, and TM4SF3 proteins in prostate cancer
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Androgen receptor (AR) and its constitutively active splice variant, AR Variant 7 (AR-V7), regulate genes essential for the development and progression of prostate cancer. Degradation of AR and AR-V7 by the ubiquitination proteasomal pathway is important for t... ...
