Exercise-Induced MYC as an Epigenetic Reprogramming Factor That Combats Skeletal Muscle Aging
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Of the "Yamanaka factors" Oct3/4 , Sox2 , Klf4 , and c-Myc (OSKM), the transcription factor c-Myc ( Myc ) is the most responsive to exercise in skeletal muscle and is enriched within the muscle fiber. We hypothesize that the pulsatile induction of MYC protein ... ...
