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Observational Study Drug and alcohol dependence. 2024 Mar 1:256:111122. doi: 10.1016/j.drugalcdep.2024.111122 Q13.62025

Comparison of transdermal alcohol concentration and self-reported alcohol consumption in people with alcohol dependence attending community alcohol treatment services

社区酒精治疗服务机构中的酒精依赖者透皮酒精浓度与自述饮酒量的比较研究 翻译改进

Eileen Brobbin  1, Paolo Deluca  2, Simon Coulton  3, Stephen Parkin  2, Colin Drummond  2

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作者单位

  • 1 National Addiction Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. Electronic address: eileen.brobbin@kcl.ac.uk.
  • 2 National Addiction Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
  • 3 Centre for Health Service Studies, University of Kent, Canterbury, UK.
  • DOI: 10.1016/j.drugalcdep.2024.111122 PMID: 38367536

    摘要 Ai翻译

    Aim: We aimed to assess the accuracy and wearability of a transdermal alcohol sensor (TAS) (BACtrack Skyn) with people currently receiving treatment at alcohol services.

    Method: A mixed methods observational study involving three NHS alcohol services in south London was conducted. All participants (7=male, 9=female) wore a TAS for 1 week and met with the researcher every other weekday to complete the TAS data download and a TimeLine Follow Back (TLFB). At the end of the week, a post-wear survey was completed. Transdermal Alcohol Concentration (TAC) from the TAS was compared to the TLFB. Post-wear survey responses, attendance voucher incentives and descriptive TAS data (removals, missing and skin temperature data) were analysed. We investigated different drinking event thresholds changing the criteria of TAC level and length of time TAC was increased and analysed each drinking threshold sensitivity, specificity, positive and negative predicative values, and percentage accuracy classification.

    Results: The TAS recorded the number of alcohol-drinking days with a high degree of accuracy compared to the TLFB as gold-standard. However, of the participation time of the 16 participants, 14.5% of the TAS data was missing in output and 16.4% of the recorded data suggests the TAS was not currently being worn. Of the data recorded, in line with the drinking event threshold of >15 ug/l TAC, >15minutes, we found that sensitivity = 93%, specificity = 84% and a Pearson correlation of r(16) =.926, p = <.001, BCa 95% CI [.855 -.981]. The threshold with the highest accuracy was TAC>15 ug/l, >60minutes which classified alcohol events with 90% accuracy, AUC =.910, sensitivity = 90%, specificity = 96%. The post-wear survey reported that most participants found it comfortable and that wearing it did not interfere with daily activities. Six participants reported side effects, including itching and a rash, but these would not deter them from wearing it again with all six reporting they would wear the TAS again and for longer than one week.

    Conclusions: The TAS did not capture every drinking event that was self-reported but maintained a high correlation. There were instances of missing TAS data and TAS removals. Overall, our findings would support the acceptability and feasibility of TAS as a tool that could be used in clinical settings for objective alcohol monitoring with patients being responsible for the TAS.

    Keywords: alcohol; alcohol dependence; alcohol monitoring; alcohol treatment.

    Keywords:alcohol dependence

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    期刊名:Drug and alcohol dependence

    缩写:DRUG ALCOHOL DEPEN

    ISSN:0376-8716

    e-ISSN:1879-0046

    IF/分区:3.6/Q1

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    Comparison of transdermal alcohol concentration and self-reported alcohol consumption in people with alcohol dependence attending community alcohol treatment services