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PEDF inhibits VEGF-induced vascular leakage through binding to VEGFR2 in acute myocardial infarction

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Pigment epithelium-derived factor (PEDF) could bind to vascular endothelial growth factor receptor 2 (VEGFR2) and inhibit its activation induced by VEGF. But how PEDF affects VEGFR2 pathway is still poorly understood. In this study, we elucidated the precise m... ...