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An epitope-tagged Swd2 reveals the different requirements of Swd2 concentration in H3K4 methylation and viability

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Swd2/Cps35 is a common component of the COMPASS H3K4 methyltransferase and CPF transcription termination complex in Saccharomyces cerevisiae. The deletion of SWD2 is lethal, which results from transcription termination defects in snoRNA genes. This study isola... ...