PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
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DNA double-strand breaks (DSBs) are repaired at DSB sites. How DSB sites assemble and how broken DNA is prevented from separating is not understood. Here we uncover that the synapsis of broken DNA is mediated by the DSB sensor protein poly(ADP-ribose) (PAR) po... ...
