首页 正文

Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair

{{output}}
During transcription-coupled DNA repair (TCR), RNA polymerase II (Pol II) transitions from a transcriptionally active state to an arrested state that allows for removal of DNA lesions. This transition requires site-specific ubiquitylation of Pol II by the CRL4... ...