Clearance of extracellular human amyloid-β aggregates in C. elegans by nutraceutical and pharmaceutical interventions
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Numerous anti-amyloid therapies have seen recent clinical development and approval, such as the monoclonal antibodies aducanumab and lecanemab. However, in Alzheimer's disease patients, amyloid-β (Aβ) plaques are found embedded in the extracellular matrix an... ...