首页 正文

Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBPα

{{output}}
Pioneer transcription factors are vital for cell fate changes. PU.1 and C/EBPα work together to regulate hematopoietic stem cell differentiation. However, how they recognize in vivo nucleosomal DNA targets remains elusive. Here we report the structures of the... ...