Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML
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The immune checkpoint leukocyte immunoglobulin-like receptor B4 (LILRB4) is found specifically on the cell surface of acute monocytic leukemia (monocytic AML), an aggressive and common subtype of AML. We have developed a humanized monoclonal IgG1 LILRB4-blocki... ...
