Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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The therapeutic potential for human type 2 innate lymphoid cells (ILC2s) has been underexplored. Although not observed in mouse ILC2s, we found that human ILC2s secrete granzyme B (GZMB) and directly lyse tumor cells by inducing pyroptosis and/or apoptosis, wh... ...
