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CTG18.1 expansion in transcription factor 4 (TCF4) in corneal graft failure: preliminary study

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Fuchs endothelial corneal dystrophy (FECD) is caused by a corneal endothelial cell loss, leading to corneal edema and visual impairment. The most significant genetic risk factor for FECD is an expansion of the CTG18.1 locus in transcription factor 4 (TCF4). Th... ...