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An acyl-CoA thioesterase is essential for the biosynthesis of a key dauer pheromone in C. elegans

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Methyl ketone (MK)-ascarosides represent essential components of several pheromones in Caenorhabditis elegans, including the dauer pheromone, which triggers the stress-resistant dauer larval stage, and the male-attracting sex pheromone. Here, we identify an ac... ...