The SWI/SNF Complex: A Frequently Mutated Chromatin Remodeling Complex in Cancer
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The switch/sucrose non-fermenting (SWI/SNF) chromatin remodeling complex is a global regulator of gene expression known to maintain nucleosome-depleted regions at active enhancers and promoters. The mammalian SWI/SNF protein subunits are encoded by 29 genes an... ...
