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Engineered In Vitro Tumor Model Recapitulates Molecular Signatures of Invasion in Glioblastoma

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Glioblastoma stem cells (GSCs) play an important role in the invasive nature of glioblastoma (GBM); yet, the mechanisms driving this behavior are poorly understood. To recapitulate tumor invasion in vitro, we developed a GBM tumor-mimetic hydrogel using extrac... ...