SIRT2 overexpression decreases remifentanil-stimulated post-surgical hyperalgesia via microglia
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Remifentanil (Remi)-induced hyperalgesia is a serious but common postoperative clinical problem. Sirtuin 2 (SIRT2) is essential in the pathogenetic mechanisms of several neurological disorders. However, whether SIRT2 contributes to the modulation of Remi-induc... ...
