Fibril core regions in engineered α-synuclein dimer are crucial for blocking of fibril elongation
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Synucleinopathies like Parkinson's disease are neurodegenerative diseases which are associated with the deposition of fibrillar aggregates of the endogenous protein α-synuclein (α-syn). The inhibition of the elongation of α-syn fibrils is of great scientifi... ...
