Computationally Designed Molecules Modulate ALS-Related Amyloidogenic TDP-43307-319 Aggregation
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Abnormal cytosolic aggregation of TAR DNA-binding protein of 43 kDa (TDP-43) is observed in multiple diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration, and Alzheimer's disease. Previous studies have shown that TDP-43307... ...
