A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM
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Retinoic acid (RA) induces an atrial phenotype in human induced pluripotent stem cells (hiPSCs), but expression of atrium-selective currents such as the ultrarapid (IKur) and acetylcholine-stimulated K+ current is variable and less than in the adult human atri... ...