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A Nef Precursor or Benign Counterpart: High Prevalence of Healthy Subjects with Antibody Reactivity to the C3-Convertase

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There are two anticonvertase antibody populations—Nephritic Factors which cause complement dysregulation and C3CAbs which do not.C3CAbs are highly prevalent in the healthy adult population (>95% prevalence).C3CAbs suggest a direction of study to determine th... ...