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Frontiers in microbiology. 2023 Oct 6:14:1271733. doi: 10.3389/fmicb.2023.1271733 Q14.52025

Global genomic epidemiology of chromosomally mediated non-enzymatic carbapenem resistance in Acinetobacter baumannii: on the way to predict and modify resistance

染色体介导的非酶卡巴_pen_耐药表型在鲍曼不动杆菌中的全球基因组流行病学:预测和改变耐药性的方法 翻译改进

Wedad M Nageeb  1, Nada AlHarbi  2, Amani A Alrehaili  3, Shadi A Zakai  4, Ahmed Elfadadny  5, Helal F Hetta  6

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作者单位

  • 1 Department of Medical Microbiology and Immunology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
  • 2 Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • 3 Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
  • 4 Department of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
  • 5 Department of Animal Internal Medicine, Faculty of Veterinary Medicine, Damanhour University, Damanhour, El-Beheira, Egypt.
  • 6 Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • DOI: 10.3389/fmicb.2023.1271733 PMID: 37869654

    摘要 Ai翻译

    Introduction: Although carbapenemases are frequently reported in resistant A. baumannii clinical isolates, other chromosomally mediated elements of resistance that are considered essential are frequently underestimated. Having a wide substrate range, multidrug efflux pumps frequently underlie antibiotic treatment failure. Recognizing and exploiting variations in multidrug efflux pumps and penicillin-binding proteins (PBPs) is... ...点击完成人机验证后继续浏览
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    期刊名:Frontiers in microbiology

    缩写:FRONT MICROBIOL

    ISSN:N/A

    e-ISSN:1664-302X

    IF/分区:4.5/Q1

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    Global genomic epidemiology of chromosomally mediated non-enzymatic carbapenem resistance in Acinetobacter baumannii: on the way to predict and modify resistance