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Progesterone and cAMP synergistically induce SHP2 expression via PGR and CREB1 during uterine stromal decidualization

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Decidualization of endometrial stroma is a key step in embryo implantation and its abnormality often leads to pregnancy failure. Stromal decidualization is a very complex process that is co-regulated by estrogen, progesterone and many local factors. The signal... ...