Mechanism and Selectivity of Copper-Catalyzed Bromination of Distal C(sp3)-H Bonds
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Unactivated C(sp3)-H bonds are the most challenging substrate class for transition metal-catalyzed C-H halogenation. Recently, the Yu group [Liu, T.; Myers, M. C.; Yu, J. Q. Angew. Chem., Int. Ed.2017, 56 (1), 306-309] has demonstrated that a CuII/phenanthroli... ...