Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis
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Substance use disorder remains a major challenge, with an enduring need to identify and evaluate new, translational targets for effective treatment. Here, we report the upregulation of Hypoxia-inducible factor-1α (HIF-1α) expression by roxadustat (Rox), a dr... ...
