Exploring the Barriers in the Aggregation of a Hexadecameric Human Prion Peptide through the Markov State Model
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The prefibrillar aggregation kinetics of prion peptides are still an enigma. In this perspective, we employ atomistic molecular dynamics (MD) simulations of the shortest human prion peptide (HPP) (127GYMLGS132) at various temperatures and peptide concentration... ...
