In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity
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Chimeric antigen receptor T (CAR T) cell immunotherapy is successful at treating many cancers. However, it often induces life-threatening cytokine release syndrome (CRS) and neurotoxicity. Here, we show that in situ conjugation of polyethylene glycol (PEG) to ... ...
