A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature
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Background: The Fe (II)- and α-ketoglutarate-dependent AlkB family dioxygenases are implicated in nucleotide demethylation. AlkB homolog1 (ALKBH1) is shown to demethylate DNA adenine methylation (6mA) preferentially from single-... ...
