Propranolol reduces the accumulation of cytotoxic aggregates in C9orf72-ALS/FTD in vitro models
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Mutations in the C9orf72 gene are the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The pathogenetic mechanisms linked to this gene are a direct consequence of an aberrant intronic expansion of a GGGGCC he... ...
