Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector
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Tn7-like transposons have co-opted CRISPR-Cas systems to facilitate the movement of their own DNA. These CRISPR-associated transposons (CASTs) are promising tools for programmable gene knockin. A key feature of CASTs is their ability to recruit Tn7-like transp... ...