The structure of the NuA4-Tip60 complex reveals the mechanism and importance of long-range chromatin modification
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Histone acetylation regulates most DNA transactions and is dynamically controlled by highly conserved enzymes. The only essential histone acetyltransferase (HAT) in yeast, Esa1, is part of the 1-MDa NuA4 complex, which plays pivotal roles in both transcription... ...
