Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions
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The RhoGEF Trio is a large multi-domain protein and an activator of the small GTPases Rac1, RhoG, and RhoA. Although Trio has been implicated in many cellular mechanisms like leukocyte transendothelial migration, cell-cell junction stability, lamellipodia form... ...