Structural arrangement of the active back-to-back dimer in N-glycosylated ErbB receptors is regulated by heterodimerization
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The human epidermal growth factor receptor (EGFR/ErbB) family consists of four members (ErbB1-4) and belongs to the superfamily of receptor tyrosine kinases (RTKs). The ErbB family members participate in multiple cellular pathways and are the key players in se... ...
