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Possible impact of HLA class I and class II on malignancies driven by a single germ-line BRCA1 mutation

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This study provides the first immunogenetic preliminary evidence that specific human leucocyte antigen (HLA) class I and class II alleles and haplotypes may be relevant for BRCA1 c.5263_5264insC driven oncogenesis. Observed HLA associations might have practica... ...