Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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The immune checkpoint protein PD-L1 plays critical roles in both immune system homeostasis and tumor progression. Impaired PD-1/PD-L1 function promotes autoimmunity and PD-L1 expression within tumors promotes immune evasion. If and how changes in metabolism or... ...
