Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction
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Speckle-type pox virus and zinc finger (POZ) protein (SPOP), a substrate recognition adaptor of cullin-3 (CUL3)/RING-type E3 ligase complex, is investigated for its role in cardiac fibrosis in our study. Cardiac fibroblasts (CFs) activation was achieved with T... ...
