Enhancing the functional maturity of hiPSC-derived cardiomyocytes to assess inotropic compounds
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Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) present an attractive in vitro platform to model safety and toxicity assessments-notably screening pro-arrhythmic compounds. The utility of the platform is stymied by a hiPSC-CM contractile... ...