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Activity of sotorasib against brain metastases from NSCLC harboring KRAS p.G12C mutation: a case report

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In the CodeBreaK 100 phase 2 study, sotorasib was active for patients with metastatic non-small cell lung cancer (NSCLC) harboring Kirsten rat sarcoma viral oncogene homologue (KRAS) p.G12C mutation. However, patients with untreated and/or active brain metasta... ...