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Importance of Kv Distribution in Freeze Drying Part I: A Holistic Model to Predict Changes in Kv Bimodal Distribution as a Function of Pressure

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Measurement of heat transfer coefficients (Kv) is an important part of freeze-dryers characterization and as well a necessary step for executing any modelling. In most cases only an average value of Kv is calculated, or an average value of center and edge vial... ...