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SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence

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Thoracic aortic aneurysms (TAAs) develop asymptomatically and are characterized by dilatation of the aorta. This is considered a life-threating vascular disease due to the risk of aortic rupture and without effective treatments. The current understanding of th... ...