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A Glimpse of the Structural Biology of the Metabolism of Sphingosine-1-Phosphate

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As a key sphingolipid metabolite, sphingosine-1-phosphate (S1P) plays crucial roles in vascular and immune systems. It regulates angiogenesis, vascular integrity and homeostasis, allergic responses, and lymphocyte trafficking. S1P is interconverted with sphing... ...