Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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Inhibition of protein-protein interactions (PPIs) via designed peptides is an effective strategy to perturb their biological functions. The Elongin BC heterodimer (ELOB/C) binds to a BC-box motif and is essential for cancer cell growth. Here, we report a pepti... ...
