Serotonergic circuit dysregulation underlying autism-related phenotypes in BTBR mouse model of autism
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The inbred mouse strain, BTBR T+Itpr3tf/J (BTBR), possesses neuronal and circuit abnormalities that underlie atypical behavioral profiles resembling the major symptoms of human autism spectrum disorder (ASD). Forebrain serotonin (5-HT) transmission has been im... ...
