MICU1 controls the sensitivity of the mitochondrial Ca2+ uniporter to activators and inhibitors
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Mitochondrial Ca2+ homeostasis loses its control in many diseases and might provide therapeutic targets. Mitochondrial Ca2+ uptake is mediated by the uniporter channel (mtCU), formed by MCU and is regulated by the Ca2+-sensing gatekeeper, MICU1, which shows ti... ...
