FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth
{{output}}
Continuous de novo fatty acid synthesis is required for the biosynthetic demands of tumor. FBXW7 is a highly mutated gene in CRC, but its biological functions in cancer are not fully characterized. Here, we report that FBXW7β, a FBXW7 isoform located in the c... ...
