Indoleamine 2,3-Dioxygenase: A Novel Immunotherapeutic Target for Osteosarcoma
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Introduction: Tumour-emitted molecules induce immunosuppression in the tumour microenvironment. An immunosuppressive enzyme, indoleamine 2,3-dioxygenase (IDO/IDO1), facilitates immune escape in several malignant tumours, includin... ...