mRNA produced by VSW-3 RNAP has high-level translation efficiency with low inflammatory stimulation
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In vitro preparation of mRNA is a key step for mRNA therapeutics. The widely used T7 RNA polymerase (RNAP) was shown to have many by-products during in vitro transcription (IVT) process, among which double-stranded RNA (dsRNA) is the major by-product to activa... ...
