Diverse but desolate landscape of gut microbial azoreductases: A rationale for idiopathic IBD drug response
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Prodrugs reliant on microbial activation are widely used but exhibit a range of efficacies that remain poorly understood. The anti-inflammatory compound 5-aminosalicylic acid (5-ASA), which is packaged in a variety of azo-linked prodrugs provided to most Ulcer... ...