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Review Current microbiology. 2023 Apr 27;80(6):194. doi: 10.1007/s00284-023-03304-1 Q32.62025

Repurposing of RAS-Pathway Mediated Drugs for Intestinal Inflammation Related Diseases for Treating SARS-CoV-2 Infection

用于治疗SARS-CoV-2感染的肠道炎症相关疾病的RAS通路介导药物再利用研究 翻译改进

Anupriya Sinha  1, Raghavendra Goud Vaggu  1, Ramakrushna Swain  1, Srinivas Patnaik  2

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作者单位

  • 1 School of Biotechnology, KIIT University, Campus-XI, Bhubaneswar, Odisha, 751024, India.
  • 2 School of Biotechnology, KIIT University, Campus-XI, Bhubaneswar, Odisha, 751024, India. srinivas.patnaik@kiitbiotech.ac.in.
  • DOI: 10.1007/s00284-023-03304-1 PMID: 37106165

    摘要 Ai翻译

    Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is an emerging zoonotic virus, which causes Coronavirus Disease 2019 (COVID-19). Entry of coronaviruses into the cell depends on binding of the viral spike (S) proteins to cellular receptors Angiotensin-converting enzyme 2 (ACE2). The virus-mediated reduction of ACE2/Ang1-7 causes flooding of inflammatory cytokines. A similar scenario of hyper immunologic reaction has been witnessed in the contex... ...点击完成人机验证后继续浏览
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    期刊名:Current microbiology

    缩写:CURR MICROBIOL

    ISSN:0343-8651

    e-ISSN:1432-0991

    IF/分区:2.6/Q3

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    Repurposing of RAS-Pathway Mediated Drugs for Intestinal Inflammation Related Diseases for Treating SARS-CoV-2 Infection