Significance of PBRM1 mutation in disease progress and drug selection in clear cell renal cell carcinoma
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Clear cell renal cell carcinoma (ccRCC) is the predominant type of kidney cancer, and the mutation of PBRM1 (Polybromo 1) gene is a commonly observed genetic alteration. The high frequency of PBRM1 mutation in ccRCC suggests its potential use as a biomarker fo... ...
